In a case series of 3 patients, Baum et al also suggested an association between hepatic adenomas and OCPs.
[ 3 ] Klatskin
[ 4 ] and Rooks et al
[ 5 ] reported that the greatest risk occurs in women older than age 30 years taking OCPs for longer than 5 years, but in 10% of patients, exposure may be as short as 6-12 months. Cherqui et al also reported that adenomas are occasionally diagnosed after discontinuation of OCPs.
[ 6 ]
Hepatocellular adenoma (also known as hepatic adenoma or hepadenoma ) is a rare, benign liver tumor. It most commonly occurs in people with elevated systemic levels of estrogen, classically in women taking estrogen-containing oral contraceptive medication.