There are no symptoms associated with the lesion itself,  although many and varied symptoms and signs may be associated with the underlying cause of immunosuppression. The lesion is a white patch, which almost exclusively occurs on the lateral surfaces of the tongue, although rarely it may occur on the buccal mucosa , soft palate , pharynx or esophagus .  The lesion may grow to involve the dorsal surface of the tongue. The texture is vertically corrugated ("hairy") or thickly furrowed and shaggy in appearance. 
Leukoplakia is a white or gray patch that develops on the tongue , the inside of the cheek, or on the floor of the mouth . It is the mouth 's reaction to chronic irritation of the mucous membranes of the mouth . Leukoplakia patches can also develop on the female genital area; however, the cause of this is unknown.